C4-Complement, plasma or serum
Alternate test name
Complement
Lab area
Clinical Biochemistry - General
Method and equipment
Abbott Ci4100
Expected turn-around time
STAT/ Urgent: 4 Hours
Routine: 24 Hours
Specimen type
Serum or plasma
Specimen requirements
SST Tube preferred, PST Tube is acceptable
Storage and transportation
Frozen
Shipping information
The Hospital for Sick Children
Rapid Response Laboratory
555 University Avenue, Room 3642
Toronto, ON
Canada
M5G 1X8
Phone: 416-813-7200
Toll Free: 1-855-381-3212
Hours: 7 days/week, 24 hours/day
Requisition
Background and clinical significance
Complement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human leukocyte antigen (HLA) system. It serves a number of critical functions in immunity, tolerance, and autoimmunity with the other numerous components. Furthermore, it is a crucial factor in connecting the recognition pathways of the overall system instigated by antibody-antigen (Ab-Ag) complexes to the other effector proteins of the innate immune response.
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Customer Service
Toll Free: 1-855-381-3212
Local: 416-813-7200