Kingella kingae PCR - Biopsy
Alternate test name
Septic arthritis, osteoarthritis infection, bacteremia, culture negative endocarditis, HACEK
Gene name / Alternate gene name
RTX toxin gene (rtxB)
Lab area
Microbiology - Molecular
Method and equipment
Real-Time Polymerase Chain Reaction
Specimen type
- Synovial biopsy
- Bone biopsy
- Vegetation (heart valve)
Specimen requirements
- send in screw top container
Storage and transportation
- All specimens must be shipped on dry ice.
- Exception: specimens that arrive at SickKids within 24hrs from time of collection can be shipped on ice packs.
Special requirements
Specimen Sources:
- Synovial tissue
- Bone
- Heart valve or vegetations
Requisition
Background and clinical significance
Kingella kingae is an important cause of septic arthritis in young children. Its fastidious nature makes it difficult to culture. K. kingae is also an important cause of culture negative endocarditis (HACEK group) in children and adults .
Disease condition
- Septic arthritis
- Endocarditis
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