Sonia Grandi

Sonia Grandi, PhD, is a Scientist at SickKids Research Institute and an Assistant Professor at the University of Toronto in the Division of Epidemiology at the Dalla Lana School of Public Health. She completed her PhD in Epidemiology at McGill University in the Department of Epidemiology, Biostatistics, and Occupational Health and a postdoctoral fellowship at the Eunice Kennedy Shriver National Institutes of Child Health and Human Development at the National Institutes of Health. Her work focused on the consequences of pregnancy complications on long-term maternal cardiovascular disease and mortality and strategies for early identification and screening of at-risk women.

Research

Dr. Grandi’s research focuses on the short- and long-term influence of preconception and perinatal exposures on the health of mothers and children, with a focus on cardiometabolic health. Her research interests include understanding how pregnancy complications and interventions designed to reduce those complications, impact the health of mothers and infants, the safety and effectiveness of medications taken during pregnancy on the health of mothers and their children among women with chronic conditions, and understanding inequities in severe maternal morbidity and mortality and strategies to identify women at highest risk. As a methodologist, Dr. Grandi is interested in the application of contemporary methods and leveraging administrative health data to help inform clinical practice.

Education and experience

• 2020–2021: Postdoctoral Fellowship, Eunice Shriver Kennedy National Institute of Child Health and Human Development, National Institutes of Health Research, Epidemiology Branch, Bethesda, MD, USA
• 2013–2019: PhD, Epidemiology, Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada
• 2003–2007: M.Sc., Nutrition, School of Human Nutrition, McGill University, Montreal, QC, Canada
• 1996–2001: B.Sc., Human Biology, University of Toronto, Toronto, ON, Canada

Achievements

• 2024-2027: Society for Epidemiologic Research, Co-Chair of the Mentorship Committee
• 2024 Rising Star Award, Society for Pediatric and Perinatal Epidemiologic Research
• 2023–2026: Junior Editor, Paediatric and Perinatal Epidemiology Journal
• 2020–2021: Society for Pediatric and Perinatal Epidemiologic Research, Elected Member of the Executive Committee
• 2019: Lady Davis Institute of Medical Research, Paper of the Month, Montreal, QC, Canada
• 2019: Poster Presentation Prize, First Place: Canadian National Perinatal Research Meeting
• 2018: Top three most downloaded articles in the last two years, Journal of Pediatric and Perinatal Epidemiology
• 2017: Oral Presentation Prize, First Place: Department of Epidemiology, Biostatistics, and Occupational Health Research Day, McGill University
• 2015: Trudy Bush Fellowship for Cardiovascular Disease Research in Women’s Health, American Heart Association

Funding

• 2024–2028: The CAnadian Mother-Child Initiative - knowledge mobilization from COnception to adulthood - CAMCCO-Outreach. Co-Applicant. Canadian Institutes of Health Research, National Women’s Health Research Initiative: Pan Canadian Women’s Health Coalition Hub. $840,000 CAD. Principal Applicant: Anick Berard.
• 2024–2027: Pregnancy Outcomes and Care of Women with Physical-Mental Multimorbidity. Co-Applicant, Canadian Institutes of Health Research – Project Grant. $558,112 CAD. Principal Applicant: Hilary Brown.
• 2024–2027: PREGTRIAL (Inclusion of PREgnant and lactatinG people in clinical TRIALs). Co-Applicant. Canadian Institutes of Health Research - National Women’s Health Research Initiative - Innovation Fund - Healthcare implementation research – Operating Grant. $598,561 CAD. Principal Applicant: Natalie Dayan.
• 2024–2026: Exploring BIOlogic drug use to inform a National pharmacoepidemiologIC safety study in pregnant WOMEN (BIONIC-WOMEN). Principal Investigator. Canadian Foundation for Women’s Health – Research Grant. $10,000 CAD. Co-Principal Investigator: Cristina Longo.
• 2024–2025: BIOlogic drug safety and effectiveness International pharmacoepidemiologIC study in pregnant women with autoimmune disease and asthma and their CHILDREN (BIONIC). Principal Investigator. Canadian Institutes of Health Research – Human Development, Child and Youth Health - Early Career Support. $100,000 CAD. Co-Principal Investigator: Cristina Longo.
• 2023–2025: Aspirin and severe maternal morbidity and mortality and adverse perinatal outcomes. Principal Investigator. Canadian Institutes of Health Research – Project Grant. $294,526 CAD. Co-Principal Investigator: Joel Ray
• 2023–2025: Childhood Grief in Canada: Understanding Prevalence, Demographics, Disparities, and Quality Indicators for Service Provision. Co-Investigator. Canadian Institutes of Health Research – Operating Grant. $50,000 CAD. Principal Investigator: Kimberley Widger
• 2022: Cardiometabolic Health of Mothers with a Sick Child. Co-Principal Investigator. Data Sciences Institute, University of Toronto – Data Access Grant. $10,000 CAD. Co-Principal Investigator: Eyal Cohen

1. Grandi SM, Yu YH, Reynier P, Platt RW, Yu OHY, Filion KB. Levothyroxine initiation and the risk of pregnancy loss among pregnant women with subclinical hypothyroidism: An observational study emulating a target trial. Paediatric and Perinatal Epidemiology - Special Issue on Perinatal and Paediatric Pharmacoepidemiology. Paediatr Perinat Epidemiol. 2024 Aug;38(6):470-481. doi: 10.1111/ppe.13015. Epub 2023 Nov 3.
2. Chiodo S, Tailor L, Platt RW, Wood ME, Grandi SM. Emulating a Target Trial in Perinatal Pharmacoepidemiology: Challenges and Methodological Approaches. Invited Review - Current Epidemiology Reports. November 2023. doi:10.1007/s40471-023-00339-7.
3. Sharma G, Ipek EG, Grandi SM. The Impact of Hypertensive Disorders of Pregnancy on Cardiovascular Outcomes: Flying Under the Radar. Invited Editorial Comment. J Am Coll Cardiol. 2022 May 17;79(19):1914-1916. doi: 10.1016/j.jacc.2022.03.334.
4. Grandi SM, Hinkle SN, Mumford SL, Sjaarda LA, Grantz KL, Mendola P, Mills JL, Pollack AZ, Yeung E, Zhang C, Schisterman EF. Long-term mortality in women with pregnancy loss and modification by race/ethnicity. Am J Epidemiol. 2022 Mar 24;191(5):787-799. doi: 10.1093/aje/kwac023.
5. Grandi SM, Filion KB, Yoon S, Ayele HT, Doyle CM, Hutcheon JA, Gore GC, Smith GN, Ray J, Nerenberg K, Platt RW. Cardiovascular Disease-Related Morbidity and Mortality in Women with a History of Pregnancy Complications: A Systematic Review. Circulation. 2019; 139:1069-1079.

See Sonia Grandi's Google Scholar profile. 
See a full list of Sonia Grandi's publications on PubMed.