Jean-Philippe Julien

Title: Senior Scientist, Molecular Medicine

Designations: PhD

Phone: 416-813-7654 ext. 309424

Email: jean-philippe.julien@sickkids.ca

Fax: 416-813-5993

U of T Positions: Associate Professor, Departments of Biochemistry and Immunology

Chair Positions: Canada Research Chair, Structural Immunology

Biography

Jean-Philippe Julien received his B.Sc. from McGill University, obtained his PhD from the University of Toronto, and trained as a post-doctoral fellow at The Scripps Research Institute. In Fall 2014, he joined the Molecular Medicine Program at SickKids Research Institute and the Departments of Biochemistry and Immunology at the University of Toronto where he leads a team of multi-disciplinary researchers. His laboratory focuses on the molecular characterization of antibodies by studies of their interactions with cell surface receptors in therapeutic development, and with pathogens guiding vaccine design primarily against Plasmodium falciparum malaria, HIV-1 and COVID-19. Notably, he is a Canada Research Chair in Structural Immunology, a CIFAR Azrieli Global Scholar and a Member of the College of the Royal Society of Canada.

Research

Surface glycoproteins on immune cells often play critical roles that directly influence responses to invading pathogens. A better understanding of their atomic structure and the three-dimensional molecular complexes they form allows us to gain insight into their specific functions. This molecular understanding provides roadmaps for scientists to design improved vaccines against pathogens of global health importance, and treatments in cancer and autoimmune diseases.

Education and experience

2005: B.Sc., Biochemistry, McGill University, Montreal, Quebec
2010: PhD, Biochemistry, University of Toronto, Toronto, Ontario
2010–2014: Post-doctoral Fellow, Integrative Structural and Computational Biology, Scripps Research Institute, USA

Achievements

2021: New Investigator Award, Canadian Society for Molecular Biosciences
2020: Young Investigator Award, Amgen
2020: W. H. and W. L. Bragg Prize, International Union of Crystallography
2020: New Investigator Award, Canadian Society for Immunology
2019: Member of the College of New Scholars, Artists and Scientists of the Royal Society of Canada, Royal Society of Canada
2019: Azrieli Global Scholar, Canadian Institute for Advanced Research
2019: Ontario Ministry of Research, Innovation and Science Early Researcher Award, Government of Ontario
2017: Young Investigator Excellence Award, Canadian Light Source
2017: Tier 2 Canada Research Chair in Structural Immunology, Canadian Institutes of Health Research

Publications

See a full list of Jean-Philippe Julien's publications