Ryan Yuen

Education and experience

• 2023–present: Associate Professor, Molecular Genetics, University of Toronto, Toronto, ON
• 2022–present: Senior Scientist, Genetics and Genome Biology, SickKids Research Institute, Toronto, ON
• 2017–2022: Scientist, Genetics and Genome Biology, SickKids Research Institute, Toronto, ON
• 2017–2023: Assistant Professor, Molecular Genetics, University of Toronto, Toronto, ON
• 2014–2017: Research Associate, Genetics and Genome Biology, SickKids, Toronto, ON 
• 2011–2014: Post-doctoral Fellow, Genetics and Genome Biology, SickKids, Toronto, ON
• 2007–2011: PhD, Medical Genetics, University of British Columbia, Vancouver, BC

1. Wen J*, Trost B*, Engchuan W*, Halvorsen M, Pallotto L, Mitina A, Ancalade N, Farrell M, Backstrom I, Guo K, Pellecchia G, Thiruvahindrapuram B, Giusti-Rodriguez P, Magnusson PKE, Gyllensten U, Hultman CM, Sullivan PF, Yuen RKC†, Szatkiewicz JP†. (2023). Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia. Molecular Psychiatry. 28: 275-482. 
2. Mojarad BA, Engchuan W, Trost B, Backstrom I, Yin Y, Thiruvahindrapuram B, Pallotto L, Khan M, Pellecchia G, Haque B, Guo K, Heung T, Costain G, Scherer SW, Marshall CR, Pearson CE, Bassett AS*, Yuen RKC*. (2022) Genome-wide tandem repeat expansions contribute to schizophrenia risk. Molecular Psychiatry. 27: 3692-3698. 
3. Mojarad BA, Yin Y, Manshaei R, Backstrom I, Costain G, Heung T, Merico D, Marshall CR, Bassett AS†, Yuen RKC†. (2021). Genome sequencing broadens the range of contributing variants with clinical implications in schizophrenia. Translational Psychiatry. 11: 84.
4. Trost B*, Engchuan W*, Nguyen CM*, Thiruvahindrapuram B*, Dolzhenko E, Backstrom I, Mirceta M, Adhami-Mojarad B, Yin Y, Dov A, Chandrakumar I, Prasolava T, Shum N, Hamdan O, Pellecchia G, Howe JL, Whitney J, Amaral DG, Anagnostou E, Elsabbagh M, Fernandez BA, Lewis SME, Szatmari P, Zwaigenbaum L, Glazer D, Hartley D, Eberle MA, Sato N, Pearson CE, Scherer SW, Yuen RKC. (2020) Genome-wide detection of DNA repeats expanded in autism. Nature. 586: 80-86
5. Dolzhenko E*, Bennett MF*, Richmond PA*, Trost B, Chen S, van Vugt JJFA, Nguyen C, Narzisi G, Gainullin VG, Gross A, Lajoie B, Taft RJ, Wasserman WW, Scherer SW, Veldink JH, Bentley DR, Yuen RKC*, Bahlo M*, Eberle MA*. (2020) ExpansionHunter Denovo: A computational method for locating known and novel repeat expansions in short-read sequencing data. Genome Biology. 21: 102. 

See a full list of Dr. Ryan Yuen's publications on PubMed or Google Scholar.